Card-20(22)-enolide, 3-[(2,6-dideoxy-3-O-methyl-β-D-ribo-hexopyranosyl)oxy]-5,14-dihydroxy-, (3β,5β)- (9CI)
periplocymarin
CAS: 32476-67-8
Molecular Formula: C30H46O8
Card-20(22)-enolide, 3-[(2,6-dideoxy-3-O-methyl-β-D-ribo-hexopyranosyl)oxy]-5,14-dihydroxy-, (3β,5β)- (9CI) - Names and Identifiers
Card-20(22)-enolide, 3-[(2,6-dideoxy-3-O-methyl-β-D-ribo-hexopyranosyl)oxy]-5,14-dihydroxy-, (3β,5β)- (9CI) - Physico-chemical Properties
| Molecular Formula | C30H46O8 |
| Molar Mass | 534.68 |
| Density | 1.27±0.1 g/cm3(Predicted) |
| Melting Point | 148° |
| Boling Point | 690.9±55.0 °C(Predicted) |
| Specific Rotation(α) | D27 +29° (c = 0.94 in 95% alcohol for the anhydr substance) |
| Solubility | Soluble in chloroform, ethyl acetate, soluble in methanol, DMSO |
| Appearance | White powder |
| pKa | 13.55±0.70(Predicted) |
| Storage Condition | 2-8℃ |
| MDL | MFCD01740198 |
| Physical and Chemical Properties | White crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from the skin. |
| In vitro study | Periplocymarin inhibits proliferation of PC3, U937, HCT-8, Bel-7402, BGC823, A549, and A2780 cell lines in vitro with IC 50 values of 0.02-0.29 µM. |
Card-20(22)-enolide, 3-[(2,6-dideoxy-3-O-methyl-β-D-ribo-hexopyranosyl)oxy]-5,14-dihydroxy-, (3β,5β)- (9CI) - Reference
| Reference Show more | 1. [IF=4.36] Lei Chen et al."Chemical profiling and the potential active constituents responsible for wound healing in Periploca forrestii Schltr."J Ethnopharmacol. 2018 Oct;224:230 2. [IF=3.414] Jinsong Li et al."Effects of Periploca forrestii Schltr on wound healing by Src meditated Mek/Erk and PI3K/Akt signals."J Ethnopharmacol. 2019 Jun;237:116 |
Card-20(22)-enolide, 3-[(2,6-dideoxy-3-O-methyl-β-D-ribo-hexopyranosyl)oxy]-5,14-dihydroxy-, (3β,5β)- (9CI) - Reference Information
| biological activity | Periplocymarin is a cardiac glycoside isolated from Periploca sepium and Periploca graeca, is a potential anti-cancer compound. |
Last Update：2024-04-09 02:00:12
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